Kikuko Amagase Selected Research

(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid

10/2007	Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors.
9/2007	Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy)benzamido)ethyl) benzoic acid (CJ-42794), a selective antagonist of prostaglandin E receptor subtype 4, on ulcerogenic and healing responses in rat gastrointestinal mucosa.

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Kikuko Amagase Research Topics

Disease

13	Ulcer 01/2018 - 07/2003
9	Stomach Ulcer (Gastric Ulcer) 01/2018 - 07/2003
7	Colitis 03/2018 - 01/2010
5	Inflammation (Inflammations) 03/2018 - 01/2016
5	Neoplasms (Cancer) 10/2017 - 04/2003
5	Body Weight (Weight, Body) 10/2017 - 05/2012
4	Mucositis 10/2017 - 05/2012
3	Pain (Aches) 01/2022 - 09/2007
3	Peptic Esophagitis (Reflux Esophagitis) 01/2018 - 04/2003
3	Diarrhea 01/2017 - 05/2012
3	Hemorrhage 12/2014 - 05/2010
3	Gastritis 01/2013 - 01/2011
3	Infections 01/2013 - 07/2003
3	Peptic Ulcer (Peptic Ulcers) 01/2013 - 04/2003
3	Arthritis (Polyarthritis) 08/2012 - 09/2007
3	Ischemia 05/2007 - 02/2006
2	Edema (Dropsy) 01/2022 - 01/2011
2	Wounds and Injuries (Trauma) 09/2017 - 08/2007
2	Duodenal Ulcer (Curling's Ulcer) 01/2013 - 11/2012
1	Hyperalgesia 01/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2022
1	Granuloma 01/2022
1	Neoplasm Metastasis (Metastasis) 12/2020
1	Crohn Disease (Crohn's Disease) 01/2020
1	Enteritis 01/2018
1	Ileus 01/2018
1	Dysbiosis 09/2017

Drug/Important Bio-Agent (IBA)

9	Indomethacin (Indometacin)FDA LinkGeneric 01/2022 - 08/2005
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 08/2005
7	AcidsIBA 01/2018 - 04/2003
7	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 10/2013 - 07/2003
5	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2018 - 02/2006
5	Fluorouracil (Carac)FDA LinkGeneric 10/2017 - 01/2009
5	Histamine (Histamine Dihydrochloride)FDA Link 12/2014 - 04/2003
5	ProstaglandinsIBA 01/2014 - 08/2005
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2012 - 07/2003
4	Dextrans (Dextran)FDA Link 01/2018 - 01/2016
4	CytokinesIBA 10/2017 - 01/2015
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2014 - 09/2007
4	Acetic Acid (Vinegar)FDA LinkGeneric 01/2008 - 07/2003
3	SodiumIBA 01/2018 - 01/2016
3	Dinoprostone (PGE2)FDA Link 01/2018 - 08/2007
3	Peroxidase (Myeloperoxidase)IBA 10/2017 - 01/2017
3	irsogladineIBA 12/2014 - 01/2013
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 08/2012 - 08/2007
3	Diphosphonates (Bisphosphonates)IBA 08/2012 - 08/2007
3	Epidermal Growth Factor (EGF)IBA 01/2011 - 08/2005
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2009 - 08/2005
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2022 - 01/2013
2	Capsaicin (Zostrix)FDA Link 03/2018 - 12/2014
2	CationsIBA 03/2018 - 01/2018
2	Substance PIBA 03/2018 - 01/2016
2	Calcitonin Gene-Related PeptideIBA 03/2018 - 01/2008
2	Dextran SulfateIBA 03/2018 - 01/2018
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2017 - 05/2012
2	Clopidogrel (Plavix)FDA Link 12/2014 - 01/2014
2	salicylhydroxamic acid (SHAM)IBA 12/2014 - 02/2006
2	geranylgeranylacetone (teprenone)IBA 12/2014 - 01/2014
2	rebamipideIBA 12/2014 - 01/2014
2	Pharmaceutical PreparationsIBA 12/2014 - 07/2003
2	Hemoglobins (Hemoglobin)IBA 12/2014 - 01/2014
2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 12/2014 - 01/2014
2	Urethane (Ethyl Carbamate)IBA 12/2014 - 02/2006
2	Proteins (Proteins, Gene)FDA Link 06/2014 - 08/2007
2	Proton Pump InhibitorsIBA 01/2014 - 11/2012
2	Protein Isoforms (Isoforms)IBA 01/2013 - 01/2007
2	Protective AgentsIBA 01/2013 - 07/2003
2	NitrogenIBA 01/2011 - 08/2007
2	Alendronate (Alendronate Sodium)FDA LinkGeneric 01/2011 - 08/2007
2	Ethanol (Ethyl Alcohol)IBA 01/2010 - 01/2008
2	rofecoxib (Vioxx)FDA Link 10/2007 - 09/2007
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2007 - 02/2006
2	(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acidIBA 10/2007 - 09/2007
1	pyrazoleIBA 01/2022
1	CarrageenanIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	Analgesics (Analgesic Drugs)IBA 01/2022
1	BenzenesulfonamidesIBA 01/2022
1	Celecoxib (Celebrex)FDA Link 01/2022
1	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 01/2020
1	AnkyrinsIBA 03/2018
1	LipopolysaccharidesIBA 01/2018
1	Coloring Agents (Dyes)IBA 01/2018
1	Evans Blue (Blue, Evans)FDA Link 01/2018
1	p38 Mitogen-Activated Protein KinasesIBA 01/2018
1	cadherin 5IBA 01/2018
1	N- (1- ((4- (2- (((2,4- dichlorophenyl)sulfonyl)amino)- 3- hydroxypropanoyl)- 1- piperazinyl)carbonyl)- 3- methylbutyl)- 1- benzothiophene- 2- carboxamideIBA 01/2018
1	Fluorescein (Funduscein)FDA LinkGeneric 01/2018
1	Interleukin-6 (Interleukin 6)IBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 09/2017
1	zaprinastIBA 09/2017
1	Pertussis ToxinIBA 09/2017
1	Fibronectins (Fibronectin)IBA 09/2017
1	ColforsinIBA 09/2017
1	pamoic acidIBA 09/2017

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 12/2020 - 04/2003
3	Anesthesia 12/2014 - 02/2006
1	Intraperitoneal Injections 12/2020
1	Transplantation 12/2020
1	Injections 09/2017